Cambridge, Mass. – Beam Therapeutics, a biotechnology company developing precision genetic medicines through base editing, today announced the appointment of Carole Ho, M.D., Chief Medical Officer and Head of Development at Denali Therapeutics, to the Company’s Board of Directors.
“Carole has a remarkable track record in developing new medicines as well as in building and leading exceptional clinical development organizations,” said John Evans, CEO of Beam Therapeutics. “The breadth and depth of her drug development expertise will be highly valuable to Beam as we advance the development of base editors as a new class of precision genetic medicines.”
“Base editing has the potential to correct point mutations and edit genes with high levels of precision and control, opening up new therapeutic strategies across many disease categories,” said Dr. Ho. “I look forward to collaborating with John and the Beam team on this exciting approach for patients.”
Dr. Ho brings to Beam more than 15 years of life sciences experience as a clinical neurologist, neuroscientist and leader in biopharmaceutical drug development. Prior to her current role as founding Chief Medical Officer and Head of Development at Denali Therapeutics, Dr. Ho served as Vice President of Early Clinical Development at Genentech. In that role, she was responsible for delivery of pivotal trial-ready drug candidates to the Roche / Genentech late-stage development groups in neurology, ophthalmology, immunology and infectious disease. During her eight-year tenure at Genentech, she held positions of increasing responsibility across both the early and late stage clinical development groups with development oversight for multiple therapeutic areas and molecules including crenezumab for Alzheimer’s disease, lampalizumab for dry age related macular degeneration, and development activities leading to the approvals of ocrelizumab for multiple sclerosis and Rituxan for Wegener’s granulomatosis and microscopic polyangiitis. Prior to Genentech, Dr. Ho was on faculty in the Department of Neurology at Stanford University and subsequently a Medical Director at Johnson and Johnson. Dr. Ho received her undergraduate degree in biochemical sciences from Harvard College and her M.D. from Cornell University. She completed her medical internship and neurology residency at Harvard and served as Chief Resident of Neurology at the Massachusetts General Hospital / Brigham and Women’s Hospital.
About Beam Therapeutics
Beam Therapeutics is developing precision genetic medicines through base editing. Founded by leading scientists in CRISPR gene editing, Beam is pursuing therapies for serious diseases using its proprietary base editing technology, which can make precise edits to single base pairs in DNA and RNA. Headquartered in Cambridge, Massachusetts, the company is backed by F-Prime Capital Partners and ARCH Venture Partners, two of the world’s leading biotech venture capital firms. For additional information, visit www.BeamTx.com.