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Manufacturing Associate, Pre-Clinical Manufacturing

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Beam Therapeutics is seeking a Manufacturing Associate for our Pre-clinical Manufacturing Team. This position will be based out of our labs in Cambridge, MA. The Pre-Clinical Manufacturing Associate will contribute to a team that is responsible for producing plasmid DNA and mRNA to support research and development activities for our gene therapy programs. The ideal candidate for this position will have experience with molecular biology and analytical techniques related to production of plasmid DNA. This individual must be capable of working effectively in a fast paced, small start-up company environment. Knowledge of GMP and regulatory requirements is preferred. Experience in laboratory automation a plus.

Responsibilities include, but are not limited to:

  • Plasmid production from 25ug-10mg scale
  • Primer design
  • Cloning
  • Running routine analytical methods
  • Maintaining a neat and orderly laboratory workspace
  • Adherence to laboratory health and safety practices
  • Drafting of laboratory protocols for production activities
  • Some opportunities for process development
  • Must be comfortable with routine/repetitive work

Basic Qualifications:

  • BS or 2+ years relevant experience
  • Molecular cloning methods including restriction enzyme, Golden Gate, Gibson Assembly, USER
  • Construct and primer design in Benchling and/or Geneious
  • Experience with plasmid extractions
  • Basic analytical techniques such as gel electrophoresis and sequencing
  • Strong organizational skills and attention to detail
  • Effective communication and coordination with people across various teams/positions
  • Strong problem solving and critical thinking skills