Company Overview:
Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform that includes a suite of gene editing and delivery technologies and is in the process of building internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of potential therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.
Position Overview:
Beam Therapeutics is in search of a self-motivated intern to join our Hematology team from June through August 2025. This is a unique opportunity to contribute to groundbreaking work in the field of gene editing and hematopoietic stem cell research.
Responsibilities:
As a member of our team, you will play a crucial role in advancing our mission. Your responsibilities will include:
- Primary Cell Culture: Engage in primary cell culture and immortalized cell line culture activities, including feedings, passaging, and freezing.
- Platform Assay Development: Participate in the development of platform assays, testing new materials and protocols to enhance our research capabilities.
- Transfection: Master the art of transfecting primary hematopoietic stem cells and cell lines with Lipid Nanoparticles (LNPs), a cutting-edge technology.
- Sample Preparation: Prepare samples for Next-Generation Sequencing (NGS) and other downstream analyses, ensuring the accuracy and integrity of our data.
- Documentation and Communication: Document your findings meticulously, summarize your studies, and present your results to internal audiences, contributing to the collective knowledge of our team.
- Continuous Learning: Embrace the opportunity to learn and adapt, acquiring new techniques and skills that make you a versatile, cross-functional asset.
Qualifications:
To excel in this role, you should possess the following qualifications:
- Educational Pursuit: Currently pursuing an MS or PhD in biology, biochemistry, biomedical engineering, or a related field of study.
- Cell Culture Proficiency : Prior experience with mammalian cell culture is required. Primary human cell culture experience is desirable. Experience in isolating primary immune cells using magnetic cell sorting is a plus.
- Flow Cytometry: Previous experience with multi-parameter flow cytometry is preferred.
- Gene Editing: Prior experience or knowledge of gene editing technologies, such as CRISPR, will be beneficial.
- Transfection: Knowledge of LNP or lipofectamine transfection protocols is a plus.
- Team Player: Thrive in a collaborative environment and feel at home working alongside a dynamic team.